Thursday, 5 September 2019

Things you should know about the best tranquilizer tramadol

Tramadol is an oral (to be swallowed and not crushed or chewed) opioid (narcotic) analgesic (pain reliever) like oxycodone or codeine. The brand names are ConZip, Ultram, FusePaq, Synapryn, Rybix, and Ryzolt. In was introduced in the wake of opioid addiction in the USA. It is considered to be the best opiate for relieving pain in adults. It is prescribed in case of severe pain where an opioid is required and no other treatments work or not tolerated. It prevents the rise of two neurotransmitters, norepinephrine, and serotonin. Tramadol was approved by the FDA in 1995 as a non-controlled analgesic but changed to a controlled substance since 1995 due to the rise in abuse. Since Aug 2014, Drug Enforcement Administration (DEA) placed Tramadol into Schedule IV of the controlled substance act. This is because the opioid overdose in the USA was on the rise.
Tramadol also comes in Generic options. Tramadol immediate-release tablets (brand name Ultram) comes in 50 mg and 100 mg. Tramadol  extended-release capsules (tramadol ER, brand name ConZip) comes in 100 mg, 150 mg, 200 mg, and 300 mg Tramadol extended-release tablets comes100, 200, and 300 mg (no brand name). Tramadol is gaining popularity as an analgesic which relieves pain faster hence the supplier worldwide is on the rise. Tramadol will work in Surgery, Serious accidents, severe health conditions. The choice of medicine depends upon the severity of the pain. Tramadol and Hydrocodone come in the form of a pill. The pill needs to be swallowed in its entirety, and not be crushed because crushing may cause overdose and overreaction inside your body.
Common side effects seen in the patients are:
  • Headache
  • itching
  • Nausea
  • vomiting
  • Constipation (can be more common in the elderly > 75 years)
  • Diarrhea
  • Heartburn
  • Dizziness
  • Sleepiness
  • Nervousness, 
  • anxiety
  • agitation
  • tiredness
  • stomach pain


Serious side effects are:
  • addiction
  • abuse
  • misuse
  • depressed breathing
  • respiratory depression
  • ultra-rapid metabolism
  • respiratory depression in children 
  • neonatal opioid withdrawal syndrome
  • effects due to drug interactions with benzodiazepines or other sedative-type (CNS depressant) drugs
  • serotonin syndrome
  • seizures
  • suicide or attempted suicide
  • adrenal insufficiency
  • severe hypotension (low blood pressure)
  • gastrointestinal adverse reactions
  • androgen deficiency
  • abnormal heart rhythms
  • severe hypersensitivity (allergic) reactions
  • withdrawal
One should take extra care when using of Tramadol in Children.  When used in children, the effects observed are, Life-threatening respiratory depression, difficult, slowed breathing. Even death has occurred in children due to tramadol. Ingestion of tramadol in children can be fatal.
The combinations which can lead to extreme sedation slowed or stopped breathing, coma and death tramadol with benzodiazepines (or any other sedative, hypnotic or tranquilizer) is
  • anti-anxiety medication, 
  • muscle relaxant, anesthetic, 
  • antipsychotic, 
  • alcohol 
  • other narcotic medications (including illegal drugs) 
One should avoid driving, operating machinery or other activities that require mental alertness until the effects of the drug are known and you are sure you can safely drive. One should do a drug interaction review each time they start a new medication, or even stop a medication, and that includes prescription drugs, herbals, over-the-counter (OTC) medicines, and supplements like vitamins. Your pharmacist can advise you on possible tramadol drug interactions, so be sure to ask.
Is buying Tramadol online is safe?

You can purchase Tramadol with a valid prescription from a doctor. If sold, without prescription then the chances are that the tramadol may not be genuine. Do not get it by mail from a foreign country. Do not order it from social media. These are illegal methods and heavily monitored. Do not get yourself into greater trouble than the urge to consume it. Many of unsolicited and fake online pharmacies/sites may scam you to buy the best tramadol for sale by taking the money and not delivering it. Make sure you are ordering from a USA online pharmacy. Importing from outside of the USA is illegal. Online medication could also be a notch down or many notches down from its original ingredients. You also require a physical handwritten prescription to order from an authentic USA borne site. You may still get lured and tempted to buy a prescription drug like Tramadol to purchase online without a physical prescription. Many such sites are available and flourishing online. Stay away as much as you can from that bogus site because you may lose money while not getting the product. Tramadol can be habit-forming. The history of drug-seeking behavior may be at greater risk of addiction.

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